SOFA Score Calculator — Sequential Organ Failure Assessment (Sepsis-3 Definition)
Calculate the SOFA score to quantify organ dysfunction in ICU patients and diagnose sepsis according to the Sepsis-3 consensus criteria.
SOFA Score Calculator
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This calculator is for informational and educational purposes. Results should be interpreted with clinical judgment and local guidelines.
What is the SOFA Score?
The SOFA score (Sequential Organ Failure Assessment, formerly Sepsis-related Organ Failure Assessment) is a validated clinical scoring system used to track a patient's status during an ICU stay and determine the extent of organ dysfunction. Formulated by the European Society of Intensive Care Medicine (ESICM) consensus meeting in 1994, the SOFA score assesses 6 organ systems: Respiration (PaO₂/FiO₂ ratio), Coagulation (platelets), Liver (bilirubin), Cardiovascular (mean arterial pressure & vasopressors), CNS (Glasgow Coma Scale), and Renal (creatinine & urine output). Each organ system is scored from 0 (normal) to 4 (severe failure), giving a maximum score of 24. Under the Sepsis-3 consensus definition (2016), Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection, operationally identified by an acute change in total SOFA score ≥ 2 points.
SOFA Score = Sum of 6 organ system scores (0–4 each). Range: 0 to 24. Acute SOFA increase ≥ 2 points defines Sepsis-3 organ dysfunction in infected patients. SOFA > 11 predicts > 50% ICU mortality.
When to Use the SOFA Score Calculator
- Daily assessment of organ failure trajectory in all ICU patients.
- Operational diagnosis of Sepsis under Sepsis-3 criteria (acute change in SOFA ≥ 2 points in suspected or confirmed infection).
- Mortality risk stratification and resource allocation in critical care medicine.
- Monitoring clinical response to ICU interventions (vasopressors, mechanical ventilation, renal replacement therapy).
SOFA Score System Breakdown (0–4 Points per System)
SOFA Total Score Formula
SOFA = Resp (0–4) + Coag (0–4) + Liver (0–4) + CV (0–4) + CNS (0–4) + Renal (0–4)
PaO₂/FiO₂ = 250 (+2), Plt = 80 (+2), Bili = 3.0 (+2), MAP = 60 (+1), GCS = 14 (+1), Cr = 2.5 (+2) → Total SOFA = 10
Variables
Respiratory (PaO₂/FiO₂) (mmHg)
0: ≥ 400 | 1: < 400 | 2: < 300 | 3: < 200 with mechanical ventilation | 4: < 100 with mechanical ventilation
Coagulation (Platelets) (×10³/µL)
0: ≥ 150 | 1: < 150 | 2: < 100 | 3: < 50 | 4: < 20
Liver (Bilirubin) (mg/dL)
0: < 1.2 | 1: 1.2–1.9 | 2: 2.0–5.9 | 3: 6.0–11.9 | 4: ≥ 12.0
Cardiovascular (MAP / Vasopressors) (mmHg / µg/kg/min)
0: MAP ≥ 70 | 1: MAP < 70 | 2: Dopamine ≤ 5 or Dobutamine (any) | 3: Dopamine > 5 OR Norepi ≤ 0.1 | 4: Dopamine > 15 OR Norepi > 0.1
CNS (Glasgow Coma Scale) (points)
0: GCS 15 | 1: GCS 13–14 | 2: GCS 10–12 | 3: GCS 6–9 | 4: GCS < 6
Renal (Creatinine / Urine Output) (mg/dL / mL/day)
0: Cr < 1.2 | 1: Cr 1.2–1.9 | 2: Cr 2.0–3.4 | 3: Cr 3.5–4.9 or UO < 500 mL/day | 4: Cr ≥ 5.0 or UO < 200 mL/day
The worst parameter value within the previous 24 hours should be used for daily SOFA scoring.
SOFA Score Mortality Risk Table
Initial and maximum SOFA scores during ICU admission correlate with in-hospital mortality.
| Range | Classification | Health Risk |
|---|---|---|
| 0–1 points | Minimal Organ Failure | < 3% ICU mortality |
| 2–5 points | Mild Organ Failure (Sepsis Threshold) | 5–15% ICU mortality |
| 6–9 points | Moderate Organ Failure | 15–30% ICU mortality |
| 10–12 points | Severe Organ Failure | 40–50% ICU mortality |
| 13–24 points | Extreme Organ Failure (MODS) | > 50–95% ICU mortality |
A delta SOFA (change in score over 48 hours) is a strong independent predictor of survival: decreasing SOFA indicates therapeutic response.
Limitations & Clinical Warnings
Requires laboratory arterial blood gas (PaO₂/FiO₂) and lab tests; quick SOFA (qSOFA) is used for rapid bedside screening outside the ICU.
GCS can be confounded by sedation in intubated ICU patients.
Does not distinguish chronic baseline organ failure (e.g. baseline CKD or cirrhosis) from acute dysfunction unless baseline SOFA is known.
Medical Disclaimer
SOFA is a descriptor of organ dysfunction severity, not a standalone diagnostic test for specific diseases.
References & Citations
- Vincent JL, Moreno R, Takala J, et al.. “The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure”. Intensive Care Medicine. 1996. 22(7): 707–710. PMID: 8844239
- Singer M, Deutschman CS, Seymour CW, et al.. “The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)”. JAMA. 2016. 315(8): 801–810. PMID: 26903338 | DOI: 10.1001/jama.2016.0287
Medically Reviewed
Reviewed by CliniqWise Clinical Advisory Board — Intensive Care Unit Panel · Last updated: 2026-08-27 · Next review: 2027-02-27
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